WASHINGTON — The Biden administration on Monday proposed strict new limits on pollution from buses, delivery vans, tractor-trailers and other heavy trucks — the first time in more than 20 years that tailpipe standards have been tightened for the biggest polluters on the road.

The new draft rule from the Environmental Protection Agency would require heavy-duty trucks to reduce emissions of nitrogen dioxide by 90 percent by 2031. Nitrogen dioxide is linked to lung cancer, heart disease and premature death.

The E.P.A. also announced plans to slightly tighten truck emissions of carbon dioxide, a greenhouse gas that is driving climate change. The new rules for nitrogen oxide pollution would apply to trucks beginning with the model year 2027, while the carbon dioxide rules would apply to trucks starting with the model year 2024.

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